AKT1 quiescent cancer cells promote solid tumor growth

نویسندگان

  • Cleidson P. Alves
  • Ipsita Dey-Guha
  • Sheheryar Kabraji
  • Albert C. Yeh
  • Nilesh P. Talele
  • Xavier Solé
  • Joeeta Chowdhury
  • Mari Mino-Kenudson
  • Massimo Loda
  • Dennis Sgroi
  • Anne-Lise Borresen-Dale
  • Hege G. Russnes
  • Kenneth N. Ross
  • Sridhar Ramaswamy
چکیده

AFFILIATIONS 1 Massachusetts General Hospital Cancer Center, Boston, Massachusetts. 2 Harvard Medical School, Boston, Massachusetts. 3 Dana-Farber Cancer Institute, Boston, Massachusetts. 4 Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway. 5 Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway. 6 Broad Institute of Harvard & MIT, Cambridge, Massachusetts. 7 Harvard Stem Cell Institute, Cambridge, Massachusetts. 8 Harvard-Ludwig Center for Cancer Research, Boston, Massachusetts. ¶ Current address: Department of Translational Genomics, University of Cologne, Cologne, Germany. ♯ Current address: Cancer Prevention and Control Program, Catalan Institute of Oncology-IDIBELL, Barcelona, Spain. * CPA and ID-G contributed equally to the work ** Correspondence to: Sridhar Ramaswamy, Massachusetts General Hospital Cancer Center, Richard B. Simches Research Building, 185 Cambridge Street, Boston, MA 02114. E-mail: [email protected] Running title: AKT1 cancer cells are necessary for optimal solid tumor growth.

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تاریخ انتشار 2017